Surflocal Travel and Tourism...Check Rates and Make Hotel Reservations Online. 1- Click on the State that you want a Hotel Reservation. 2- Choose the City you want your reservation in. 3- Select the Hotel you want. 4- Click on "Check Rates" to Book your Reservation All Countries > United States > Louisiana > Opelousas Arrival Date Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Departure Date Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Adults 1 2 3 4 Children 0 1 2 3 4 Opelousas Days Inn & Suites 5761 I-49 Service Rd. Opelousas, LA 70570 Nightly Rates (77.40 - 90.00)   3 Star 4 Sunburst Newest Days Inn in the area Easy access to I-49 Only 20 miles from Lafayette Outdoor pool Complimentary High Speed Wireless Internet Restaurants are within walking distance Smoking and Non-smoking rooms Jacuzzi suites available. Rooms wi Holiday Inn Hotel & Suites Opelousas, La 5696 I 49 N Service Road Opelousas, LA 70570 Nightly Rates (92.00 - 129.95)   3 Star The Holiday Inn Hotels and Suites Opelousas. Located in the heart of Acadiana, our hotel offers 75 luxurious guest rooms and suites. Home of the annual Yambilee Festival, preferred hotel of the Evangeline Downs Horse Racing and Casino. Opelousas offe Nearby Cities: Breaux Bridge ,  Crowley ,  Duson ,  Eunice ,  Lafayette ,  Opelousas ,  Rayne ,  Scott ,  Ville Platte Opelousas Hotel Chains Days Inn Holiday Inn Opelousas POI Hospitals/Medical Care Facilities Doctors' Hospital 2.34 miles Opelousas General Hospital 1.41 miles Museums Rural African American Museum 2.24 miles 1- Click on the State that you want a Hotel Reservation. 2- Choose the City you want your reservation in. 3- Select the Hotel you want. 4- Click on "Check Rates" to Book your Reservation