Surflocal Travel and Tourism...Check Rates and Make Hotel Reservations Online. 1- Click on the State that you want a Hotel Reservation. 2- Choose the City you want your reservation in. 3- Select the Hotel you want. 4- Click on "Check Rates" to Book your Reservation All Countries > United States > South Carolina > Seneca Arrival Date Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Departure Date Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Adults 1 2 3 4 Children 0 1 2 3 4 Seneca-Days Inn Clemson 11015 Radio Station Rd. Seneca, SC 29678 Nightly Rates (64.96 - 69.96)   3 Star Our motel is surrounded by lakes with the mountains nearby. There are numerous restaurants in the area, a cinema, shopping areas within walking distance and the hospital is only a couple of blocks. We offer a complimentary breakfast from 6-10:00AM Jameson Inn Seneca 226 Hi-Tech Road Seneca, SC 29678 Nightly Rates (67.99 - 99.99)   3 Star Featuring true Southern Hospitality, Legendary Service, white colonial design, Deluxe Breakfast, clean comfortable rooms, fitness center & sparkling pool. Close to area attractions, you will enjoy the convenience of a contemporary hotel with the char Best Western Executive Inn 511 US Highway 123 Bypas Seneca, SC 29678 Nightly Rates (72.89 - 80.99)   2 Star The Best Western Executive Inn is located on the Highway 123 bypass. Nine miles away from Lake Oconee and Clemson University, just 10 miles from Duke Power Plant. ·From: All directions. Take the U.S. Highway 123 bypass north. The Best Western Exec Nearby Cities: Clayton ,  Dillard ,  Hartwell ,  Lavonia ,  Toccoa ,  Anderson ,  Clemson ,  Easley ,  Seneca Seneca Hotel Chains Best Western Days Inn Signature/Jameson Inns Seneca POI 1- Click on the State that you want a Hotel Reservation. 2- Choose the City you want your reservation in. 3- Select the Hotel you want. 4- Click on "Check Rates" to Book your Reservation